This pig-to-human study utilized genomics technology to map out when rejection events happen. This is helping scientists to better understand the detailed molecular landscape following xenotransplantation to enable earlier interventions.
Xenotransplantation—the grating or transplanting of organs or tissues between members of different species, is not without controversy, however, the detailed analyses show that two people who received heart transplants from other species had very different reactions. These findings give us new insights about how the body’s molecules and immune system respond right after such a transplant.
This study includes authors from Providence Genomics, the Providence Molecular Genomics Lab, and Earle A. Chiles Research Institute.
Read more:
Paper: Integrative multi-omics profiling in human decedents receiving pig heart xenografts
Abstract (SABCS): Mapping inter- and intra-tumor heterogeneity in Ductal Carcinoma in situ and invasive breast cancer using integrative multi-omic profiling (May 1, 2024)
